As much as I love March Madness, I usually don't fill out a bracket because I don't take time to even do light research about the teams to make half-way intelligent picks. As a result, I'm usually in deep dookie by Sunday evening of the Second Round. But those I've talked to who did fill out a bracket are all struggling due to the parity among the teams in the tourney and the numerous upsets in the first two rounds.
I have to say that this may be the most enjoyable MM I've seen in a long time for that very reason. It's all about who's playing their best ball right now, not so much about how they played during the season. Get a hot 11 or 12 seed going up against an over-confident or sluggish 3 or 4 seed and you have an upset in the making or a nail-biter at the very least.
I do think KU and Virginia are playing the best right now and are the teams to beat. But it seems like this year, more so than any other season, this tourney is wide open and the right team can make a deep run to get to the Final Four. Should that happen, some brackets are really going to get busted.
Anyway, good luck with your picks!